Former Vice President Kamala Harris is set to deliver a powerful speech Wednesday night, offering a pointed critique of President Donald Trump as he reaches his first 100 days back in office.

Speaking at the Emerge America 20th Anniversary Gala in San Francisco, Harris will focus on what she describes as the “reckless economic policies” and “escalating crises facing America’s institutions and global leadership” under Trump’s renewed administration.

The theme of Harris’s speech, “We the People,” is expected to call for renewed civic engagement and collective action. Sources close to her team say Harris will emphasize that “no one’s coming to save us,” urging Americans to stay active in shaping the nation’s future through grassroots efforts and local leadership.

“This is not the time to sit on the sidelines. It’s the time to stand up, speak out, and get involved,” Harris is expected to say, according to advance excerpts.

Harris’s address comes at a critical moment politically: President Trump’s approval ratings have slumped, with a 55% disapproval rate, according to recent polls. Political analysts anticipate that Harris’s remarks could resonate with voters dissatisfied with the administration’s current trajectory.

This speech is also deeply personal for Harris. The Emerge network, which focuses on training Democratic women to run for office, played a crucial role in launching her political career — backing her successful 2003 campaign for San Francisco District Attorney. Her return to the Emerge stage signals both a reaffirmation of her political roots and a potential preview of her future ambitions, with speculation swirling about possible runs for California governor in 2026 or even a presidential bid in 2028.

Harris is expected to draw sharp contrasts between her vision for the country and the direction taken during Trump’s second term, framing the stakes for America’s democracy, economy, and standing in the world.

As the 2024 election aftermath continues to ripple across the country, Harris’s voice remains a powerful one — especially for those seeking a new path forward.

The Emerge America Gala will take place in San Francisco on Wednesday, April 30, with Harris’s remarks serving as the keynote address.